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Article

Hypoxia‑induced circCCDC66 promotes the tumorigenesis of colorectal cancer via the miR‑3140/autophagy pathway.

International journal of molecular medicine - 1 Dec 2020

Feng Jin, Li Zhong, Li Ling, Xie Haibin, Lu Qicheng, He Xiaozhou

Abstract excerpt

Circular RNAs (circRNAs) have been reported to be involved in the progression of colorectal cancer (CRC). However, the biological role of circCCDC66 in CRC remains unclear. Therefore, the present study aimed to elucidate the mechanisms through which circCCDC66 affects the hypoxia‑induced progression of CRC. It was found that hypoxia promoted the progression of CRC and upregulated the expression of circCCDC66....

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Identifiers

PMID: 33125087
DOI: 10.3892/ijmm.2020.4747
PMCID: PMC7595663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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