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Evaluation of extracellular vesicles and gDNA from culture medium as a possible indicator of developmental competence in human embryos

29 Oct 2020

Abstract excerpt

Human embryos generated in vitro have a high incidence of chromosomal abnormalities that negatively affect pregnancy rate. Embryos generated in vitro secrete extracellular vesicles (EVs) into the culture medium that could be used potentially as indicators of embryo competence. This research aimed to evaluate the concentration and size of EVs and their gDNA content as an indicator of developmental competence in...

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PMID: 33118919
DOI: 10.1017/s0967199420000593

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