Article
Genetic Subtype-Phenotype Analysis of Growth Hormone Treatment on Psychiatric Behavior in Prader-Willi Syndrome.
Genes - 23 Oct 2020
Montes Andrea S, Osann Kathryn E, Gold June Anne, Tamura Roy N, Driscoll Daniel J, Butler Merlin G, Kimonis Virginia E
Abstract excerpt
Prader-Willi syndrome (PWS) is a complex multisystemic condition caused by a lack of paternal expression of imprinted genes from the 15q11.2-q13 region. Limited literature exists on the association between molecular classes, growth hormone use, and the prevalence of psychiatric phenotypes in PWS. In this study, we analyzed nine psychiatric phenotypes (depressed mood, anxiety, skin picking, nail picking,...
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