Fungal and bacterial microbiome dysbiosis and imbalance of trans-kingdom network in asthma

Abstract excerpt

BACKGROUND: Fungal and bacterial microbiota play an important role in development of asthma. We aim to characterize airway microbiome (mycobiome, bacteriome) and functional genes in asthmatics and controls. METHODS: Sputum microbiome of controls, untreated asthma patients and inhaled corticosteroid (ICS) receiving patients was detected using high throughput sequencing. Metagenomic sequencing was used to examine...

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