Article
Matrix metalloproteinase-14 regulates collagen degradation and migration of mononuclear cells during infection with genotype VII Newcastle disease virus.
The Journal of general virology - 1 Jan 2021
Hu Zenglei, Gu Han, Ni Jie, Hu Shunlin, Hu Jiao, Wang Xiaoquan, Liu Xiaowen, Liu Xiufan
Abstract excerpt
Upregulation of matrix metalloproteinase (MMP)-14, a major driven force of extracellular-matrix (ECM) remodelling and cell migration, correlates with ECM breakdown and pathologic manifestation of genotype VII Newcastle disease virus (NDV) in chickens. However, the functional relevance between MMP-14 and pathogenesis of genotype VII NDV remains to be investigated. In this study, expression, biofunction and...
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