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Article

Carcinogenesis of Male Oral Submucous Fibrosis Alters Salivary Microbiomes

22 Oct 2020

Abstract excerpt

Most oral squamous cell carcinoma (OSCC) tumors arise from oral premalignant lesions. Oral submucous fibrosis (OSF), usually occurring in male chewers of betel quid, is a premalignant stromal disease characterized by a high malignant transformation rate and high prevalence. Although a relationship between the inhabited microbiome and carcinogenesis has been proposed, no detailed information regarding the oral...

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PMID: 33089709
DOI: 10.1177/0022034520968750

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