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Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods.

BMC cancer - 19 Oct 2020

Jiang Yimei, Yan Xiaowei, Liu Kun, Shi Yiqing, Wang Changgang, Hu Jiele, Li You, Wu Qinghua, Xiang Ming, Zhao Ren

Abstract excerpt

BACKGROUND: In recent years, the differences between left-sided colon cancer (LCC) and right-sided colon cancer (RCC) have received increasing attention due to the clinicopathological variation between them. However, some of these differences have remained unclear and conflicting results have been reported. METHODS: From The Cancer Genome Atlas (TCGA), we obtained RNA sequencing data and gene mutation data on 323...

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Identifiers

PMID: 33076847
DOI: 10.1186/s12885-020-07507-8
PMCID: PMC7574488

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