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Exosomes in Sepsis

9 Sept 2020

Abstract excerpt

Sepsis is a severe state of infection with high mortality. Pathogen-associated molecular patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic inflammation upon binding to pattern recognition receptors. Exosomes are endosome-derived vesicles, which carry proteins, lipids and nucleic acids, and facilitate intercellular communications. Studies have shown altered contents and...

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PMID: 33013905
DOI: 10.3389/fimmu.2020.02140

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