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Characterization of Nucleocytoplasmic Shuttling of Pseudorabies Virus Protein UL46

21 Aug 2020

Abstract excerpt

Pseudorabies virus (PRV) is the etiological agent of Aujeszky’s disease, which has caused severe economic loss in China since its re-emergence in 2011. UL46, a late gene of herpesvirus, codes for the abundant but non-essential viral phosphoproteins 11 and 12 (VP11/12). In this study, VP11/12 was found to localize both inside the nucleus and in the cytoplasm. The nuclear localization signal (NLS) of VP11/12 was...

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PMID: 32974393
DOI: 10.3389/fvets.2020.00484

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