Article
CPX-351 daunorubicin-cytarabine liposome: a novel formulation to treat patients with newly diagnosed secondary acute myeloid leukemia.
Minerva medica - 1 Oct 2020
Cafaro Alessandro, Giannini Maria B, Silimbani Paolo, Cangini Delia, Masini Carla, Ghelli Luserna Di Rorà Andrea, Simonetti Giorgia, Martinelli Giovanni, Cerchione Claudio
Abstract excerpt
Over the last few years, we assisted to an increasing knowledge about acute myeloid leukemia (AML) pathobiology. However, outcomes remain unsatisfactory particularly for adult patients over 60 years old. Not surprisingly several cases of therapy-related AML (tAML) and secondary AML, both characterized by poorer prognosis, are more common in older population. For several decades initial therapy for AML remained...
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