Article
Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001-20181.
Emerging infectious diseases - 1 Oct 2020
Stecher Melanie, Chaillon Antoine, Stephan Christoph, Knops Elena, Kohmer Niko, Lehmann Clara, Eberle Josef, Bogner Johannes, Spinner Christoph D, Eis-Hübinger Anna Maria, Wasmuth Jan-Christian, Schäfer Guido, Behrens Georg, Mehta Sanjay R, Vehreschild Jörg Janne, Hoenigl Martin
Abstract excerpt
We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy-naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shared mutation.
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