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Comparison of Sequential Testing and Next Generation Sequencing in advanced Lung Adenocarcinoma patients - A single centre experience.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2020

Dall'Olio Filippo G, Conci Nicole, Rossi Giulio, Fiorentino Michelangelo, De Giglio Andrea, Grilli Giada, Altimari Annalisa, Gruppioni Elisa, Filippini Daria M, Di Federico Alessandro, Nuvola Giacomo, Ardizzoni Andrea

Abstract excerpt

OBJECTIVES: Molecular diagnosis determines therapeutic strategies for patients with non-small-cell lung cancer - adenocarcinoma (NSCLC-A) but depends on resources availability. We compared a sequential single-gene testing algorithm to next generation sequencing in NSCLC-A to assess differences in terms of effectiveness, costs, tissue consumption and time. MATERIALS AND METHODS: We analyzed a retrospective cohort...

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PMID: 32932213
DOI: 10.1016/j.lungcan.2020.08.008

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