Article
Comparative analysis of rare EDAR mutations and tooth agenesis pattern in EDAR- and EDA-associated nonsyndromic oligodontia.
Human mutation - 1 Nov 2020
Zhang Liutao, Yu Miao, Wong Sing-Wai, Qu Hong, Cai Tao, Liu Yang, Liu Haochen, Fan Zhuangzhuang, Zheng Jinglei, Zhou Yongsheng, Feng Hailan, Han Dong
Abstract excerpt
Nonsyndromic oligodontia is a rare congenital anomaly. Mutations in the ectodysplasin A receptor (EDAR) gene are the primary cause of hypohidrotic ectodermal dysplasia but are rarely reported in nonsyndromic oligodontia. This study investigated EDAR mutations in multiplex nonsyndromic oligodontia and comparatively analyzed the EDAR- and EDA-related tooth agenesis patterns. Mutation screening was carried out using...
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