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Article

lncRNA SNHG1 attenuates osteogenic differentiation via the miR‑101/DKK1 axis in bone marrow mesenchymal stem cells.

Molecular medicine reports - 1 Nov 2020

Xiang Jie, Fu Hai-Qing, Xu Zhun, Fan Wei-Jie, Liu Fei, Chen Bin

Abstract excerpt

The imbalance induced by inhibition of bone mesenchymal stem cell (BMSC) osteogenic differentiation results in osteoporosis (OP); however, the underlying regulatory mechanism is not completely understood. Long non‑coding RNAs (lncRNAs) serve crucial roles in osteogenic differentiation; therefore, investigating their regulatory role in the process of osteogenic differentiation may identify a promising therapeutic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32901867
DOI: 10.3892/mmr.2020.11489
PMCID: PMC7533455

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