Article
Sequence diversity of cytotoxic T cell antigens and satellite marker analysis of Theileria parva informs the immunization against East Coast fever in Rwanda.
Parasites & vectors - 7 Sept 2020
Atuhaire David Kalenzi, Muleya Walter, Mbao Victor, Bazarusanga Thomas, Gafarasi Isidore, Salt Jeremy, Namangala Boniface, Musoke Antony Jim
Abstract excerpt
BACKGROUND: East Coast fever (ECF) caused by Theileria parva is endemic in Rwanda. In this study, the antigenic and genetic diversity of T. parva coupled with immunization and field challenge were undertaken to provide evidence for the introduction of ECF immunization in Rwanda. METHODS: Blood collected from cattle in the field was screened for T. parva using ELISA and PCR targeting the p104 gene. Tp1 and Tp2...
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