Article
Potential predictive value of SCN4A mutation status for immune checkpoint inhibitors in melanoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2020
Lin Weiyin, Lin Anqi, Li Zhefu, Zhou Chaozheng, Chen Chufeng, Chen Boliang, Lyu Qingwen, Zhang Jian, Luo Peng
Abstract excerpt
Melanoma refers to a pigmented nevus with malignant changes. The preferred treatment for primary melanoma is surgical excision and postoperative radiotherapy, but the prognosis is poor. Immune checkpoint inhibitors (ICIs) have been remarkably successful in different types of cancers, but not all cancer patients can benefit from it. Therefore, it is essential to find predictable biomarkers and improve the accuracy...
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