Article
A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants.
Proceedings of the National Academy of Sciences of the United States of America - 22 Sept 2020
Dearlove Bethany, Lewitus Eric, Bai Hongjun, Li Yifan, Reeves Daniel B, Joyce M Gordon, Scott Paul T, Amare Mihret F, Vasan Sandhya, Michael Nelson L, Modjarrad Kayvon, Rolland Morgane
Abstract excerpt
The magnitude of the COVID-19 pandemic underscores the urgency for a safe and effective vaccine. Many vaccine candidates focus on the Spike protein, as it is targeted by neutralizing antibodies and plays a key role in viral entry. Here we investigate the diversity seen in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequences and compare it to the sequence on which most vaccine candidates are...
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