Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association of the ACTN3 R577X and ACE I/D polymorphisms with athlete status in football: a systematic review and meta-analysis.

Journal of sports sciences - 1 Jan 2021

McAuley Alexander B T, Hughes David C, Tsaprouni Loukia G, Varley Ian, Suraci Bruce, Roos Thomas R, Herbert Adam J, Kelly Adam L

Abstract excerpt

The aim of this review was to assess the association of ACTN3 R577X and ACE I/D polymorphisms with athlete status in football and determine which allele and/or genotypes are most likely to influence this phenotype via a meta-analysis. A comprehensive search identified 17 ACTN3 and 19 ACE studies. Significant associations were shown between the presence of the ACTN3 R allele and professional footballer status...

Topics

Join the communities discussing this publication.

Actinin
Alleles
Genotype
Peptidyl-Dipeptidase A
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32856541
DOI: 10.1080/02640414.2020.1812195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association of the ACTN3 R577X and ACE I/D polymorphisms with athlete status in football: a systematic review and meta-analysis.PMID 32856541Read ↗

Association between ACE and ACTN3 genes polymorphisms and athletic performance in elite and sub-elite Chinese youth male football players.Semantic proximity Read ↗

Meta-analysis of genomic variants in power and endurance sports to decode the impact of genomics on athletic performance and success.Semantic proximity Read ↗

ACTN3's R577X Single Nucleotide Polymorphism Allele Distribution Differs Significantly in Professional Football Players according to Their Field Position.Semantic proximity Read ↗

ACTN3 R577X and ACE I/D gene variants influence performance in elite sprinters: a multi-cohort study.Semantic proximity Read ↗

ACTN3 R577X Gene Variant Is Associated With Muscle-Related Phenotypes in Elite Chinese Sprint/Power Athletes.Semantic proximity Read ↗

Genetic association research in football: A systematic review.Semantic proximity Read ↗

Association between Complex ACTN3 and ACE Gene Polymorphisms and Elite Endurance Sports in Koreans: A Case-Control Study.Semantic proximity Read ↗

Prevalence of Polymorphism and Post-Training Expression of ACTN3 (R/X) and ACE (I/D) Genes in CrossFit Athletes.Semantic proximity Read ↗

Nine genetic polymorphisms associated with power athlete status - A Meta-Analysis.Semantic proximity Read ↗

ACTN3 R577X Polymorphism Is Associated With the Incidence and Severity of Injuries in Professional Football Players.Semantic proximity Read ↗

Genes for elite power and sprint performance: ACTN3 leads the way.Semantic proximity Read ↗

ACTN3 R577X genotype and athletic performance in a large cohort of Japanese athletes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.