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How Tasks Change Whole-Brain Functional Organization to Reveal Brain-Phenotype Relationships.

Cell reports - 25 Aug 2020

Greene Abigail S, Gao Siyuan, Noble Stephanie, Scheinost Dustin, Constable R Todd

Abstract excerpt

Functional connectivity (FC) calculated from task fMRI data better reveals brain-phenotype relationships than rest-based FC, but how tasks have this effect is unknown. In over 700 individuals performing seven tasks, we use psychophysiological interaction (PPI) and predictive modeling analyses to demonstrate that task-induced changes in FC successfully predict phenotype, and these changes are not simply driven by...

Topics

Brain
Female
Humans
Magnetic Resonance Imaging
Male
Neural Pathways
Phenotype

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32846124
DOI: 10.1016/j.celrep.2020.108066
PMCID: PMC7469925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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