Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulation of the let‑7 family of microRNAs may promote insulin receptor/insulin‑like growth factor signalling pathways in pancreatic ductal adenocarcinoma

10 Jul 2020

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer type characterized by dysregulated cell signalling pathways and resistance to treatment. The insulin-like growth factor (IGF) signalling pathway has been identified to have a role in tumour progression and therapy resistance. However, its regulatory roles in PDAC have remained to be fully elucidated. In the present study, dysregulated microRNAs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to FOXO transcription factor regulation
Share to Growth Hormone and Insulin-like Growth Factors
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32782579
DOI: 10.3892/ol.2020.11854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulation of the let‑7 family of microRNAs may promote insulin receptor/insulin‑like growth factor signalling pathways in pancreatic ductal adenocarcinomaPMID 32782579Read ↗

Dysregulation of miRNAs Targeting the IGF-1R Pathway in Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

Functional and Potential Therapeutic Implication of MicroRNAs in Pancreatic CancerSemantic proximity Read ↗

MicroRNAs in Pancreatic Cancer: Involvement in Carcinogenesis and Potential Use for Diagnosis and PrognosisSemantic proximity Read ↗

miRNAs in pancreatic cancer progression and metastasisSemantic proximity Read ↗

Molecular Mechanisms Underlying the Role of MicroRNAs in the Chemoresistance of Pancreatic CancerSemantic proximity Read ↗

Targeting miRNA and using miRNA as potential therapeutic options to bypass resistance in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Dysregulation of key microRNAs in pancreatic cancer developmentSemantic proximity Read ↗

The complex network of miRNA and mRNA target interactions in pancreatic cancerSemantic proximity Read ↗

MicroRNA modulated networks of adaptive and innate immune response in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

MicroRNA-21 is Overexpressed in Pancreatic Cancer and a Potential Predictor of SurvivalSemantic proximity Read ↗

MicroRNA-gene signaling pathways in pancreatic cancerSemantic proximity Read ↗

A Review on the Role of MicroRNA in Biology, Diagnosis, and Treatment of Pancreatic AdenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.