Article
HDA6-dependent histone deacetylation regulates mRNA polyadenylation in Arabidopsis.
Genome research - 1 Oct 2020
Lin Juncheng, Hung Fu-Yu, Ye Congting, Hong Liwei, Shih Yuan-Hsin, Wu Keqiang, Li Qingshun Q
Abstract excerpt
Eukaryotic histone deacetylation, critical for maintaining nucleosome structure and regulating gene expression, is mediated by histone deacetylases (HDACs). Although nucleosomes have been reported to regulate mRNA polyadenylation in humans, the role of HDACs in regulating polyadenylation has not been uncovered. Taking advantage of phenotypic studies on Arabidopsis, HDA6 (one of HDACs) was found to be a critical...
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