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MicroRNAs in ankylosing spondylitis: Function, potential and challenges

1 Jan 2020

Abstract excerpt

Epigenetic mechanisms such as DNA methylation, histone modifications and non-coding RNA, are considered the essential connection between a disorder's onset and the environment, on a permissive genetic background. Among autoimmune and inflammatory-mediated disorders, Ankylosing Spondylitis (AS), a chronic arthritis of the spine, is a very good example for the weight of epigenetics' contribution. MicroRNAs (miRNAs)...

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Autoimmune and Inflammatory Disorders Research
Bone and Joint Diseases
Spondyloarthritis Studies and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32743531
DOI: 10.1016/j.jtauto.2020.100050

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