NLRP12 gene mutations and auto-inflammatory diseases: ever-changing evidence.

Abstract excerpt

Systemic auto-inflammatory diseases (SAID) are a group of rare inherited conditions characterized by a dysregulation of the immune system and associated with recurrent episodes of fever and systemic inflammation. Patients with NLRP12 variants develop a rare autosomal dominant condition known as familial cold-induced autoinflammatory syndrome (FCAS2, OMIM #611762) that has been related to several different...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cryopyrin-Associated Periodic Syndromes
• Share to Intracellular Signaling Peptides and Proteins