Additive Uncorrelated Relaxed Clock Models for the Dating of Genomic Epidemiology Phylogenies.

Abstract excerpt

Phylogenetic dating is one of the most powerful and commonly used methods of drawing epidemiological interpretations from pathogen genomic data. Building such trees requires considering a molecular clock model which represents the rate at which substitutions accumulate on genomes. When the molecular clock rate is constant throughout the tree then the clock is said to be strict, but this is often not an acceptable...

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