Article
Oxidative stress biomarkers in Fabry disease: is there a room for them?
Journal of neurology - 1 Dec 2020
Simoncini C, Torri S, Montano V, Chico L, Gruosso F, Tuttolomondo A, Pinto A, Simonetta I, Cianci V, Salviati A, Vicenzi V, Marchi G, Girelli D, Concolino D, Sestito S, Zedde M, Siciliano G, Mancuso Michelangelo
Abstract excerpt
BACKGROUND: Fabry disease (FD) is an X-linked lysosomal storage disorder, caused by deficient activity of the alpha-galactosidase A enzyme leading to progressive and multisystemic accumulation of globotriaosylceramide. Recent data point toward oxidative stress signalling which could play an important role in both pathophysiology and disease progression. METHODS: We have examined oxidative stress biomarkers...
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