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Article

Second career of a biosynthetic enzyme: Lumazine synthase as a virus-like nanoparticle in vaccine development

6 Jul 2020

Abstract excerpt

Naturally occurring and computationally ab initio designed protein cages can now be considered as extremely suitable materials for new developments in nanotechnology. Via self-assembly from single identical or non-identical protomers large oligomeric particles can be formed. Virus-like particles have today found a number of quite successful applications in the development of new vaccines. Complex chimeric...

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PMID: 32714852
DOI: 10.1016/j.btre.2020.e00494

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