RNA‐seq–based profiling of extracellular vesicles in plasma reveals a potential role of miR‐122‐5p in asthma

Abstract excerpt

To the Editor, Asthma is a heterogeneous disease encompassing several distinct sub-phenotypes with different etiologies and treatment responses,1 but we are lacking markers to differentiate patient subgroups. MicroRNAs (miRNAs) can regulate gene expression post-transcriptionally. Due to their high stability in body fluids, their easy detection, and their functional relevance in asthma, we and others have proposed...

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