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Article

Epidermal growth factor receptor deficiency: Expanding the phenotype beyond infancy.

The Journal of dermatology - 1 Aug 2020

Earl Brian R, Szybowska Marta, Marwaha Ashish, Belostotsky Vladimir, Lara-Corrales Irene, Pope Elena, Kannu Peter

Abstract excerpt

Transmembrane tyrosine kinase receptors represent a fundamental mechanism for transducing extracellular signals into the activation of signaling cascades responsible for intercellular communication, embryogenesis and tissue integrity. The epidermal growth factor receptor (EGFR) is a canonical member of this family, regarded for its dysregulated function in various malignancies. Here, we describe a young female...

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PMID: 32602142
DOI: 10.1111/1346-8138.15377

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