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LIPS method for the detection of SARS‐CoV‐2 antibodies to spike and nucleocapsid proteins

25 Jun 2020

Abstract excerpt

Profiling antibodies to SARS-CoV-2 can help to assess potential immune response after COVID-19 disease. Luciferase IP system (LIPS) assay is a sensitive method for quantitative detection of antibodies to antigens in their native conformation. We here describe LIPS to detect antibody responses to SARS-CoV-2 spike (S) and nucleocapsid (N) proteins in COVID-19 patients. The antibodies targeted both S and N fragments...

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PMID: 32584420
DOI: 10.1002/eji.202048715

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