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Article

Sequential ctDNA whole-exome sequencing in advanced lung adenocarcinoma with initial durable tumor response on immune checkpoint inhibitor and late progression.

Journal for immunotherapy of cancer - 1 Jun 2020

Giroux Leprieur Etienne, Hélias-Rodzewicz Zofia, Takam Kamga Paul, Costantini Adrien, Julie Catherine, Corjon Alexandre, Dumenil Coraline, Dumoulin Jennifer, Giraud Violaine, Labrune Sylvie, Garinet Simon, Chinet Thierry, Emile Jean-François

Abstract excerpt

BACKGROUND: Despite prolonged tumor response to immune checkpoint inhibitors (ICIs) for a subset of patients with advanced non-small cell lung cancer (NSCLC), a secondary resistance will occur for a majority of these patients. The understanding of late progression mechanisms with ICIs is important to improve future treatment strategies. METHODS: We performed whole-exome sequencing (WES) on circulating tumor DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32581058
DOI: 10.1136/jitc-2020-000527
PMCID: PMC7319709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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