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Molecular Diagnosis of COVID-19: Challenges and Research Needs

23 Jun 2020

Abstract excerpt

Molecular diagnosis of COVID-19 primarily relies on the detection of RNA of the SARS-CoV-2 virus, the causative infectious agent of the pandemic. Reverse transcription polymerase chain reaction (RT-PCR) enables sensitive detection of specific sequences of genes that encode the RNA dependent RNA polymerase (RdRP), nucleocapsid (N), envelope (E), and spike (S) proteins of the virus. Although RT-PCR tests have been...

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PMID: 32573207
DOI: 10.1021/acs.analchem.0c02060

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