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Identification of immune and non-immune cells in regenerating axolotl limbs by single-cell sequencing

17 Jun 2020

Abstract excerpt

Immune cells are known to be critical for successful limb regeneration in the axolotl (Ambystoma mexicanum), but many details regarding their identity, behavior, and function are yet to be resolved. We isolated peripheral leukocytes from the blood of adult axolotls and then created two samples for single-cell sequencing: 1) peripheral leukocytes (N = 7889) and 2) peripheral leukocytes with presumptive macrophages...

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PMID: 32562784
DOI: 10.1016/j.yexcr.2020.112149

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