Article
Nivolumab in Patients with Advanced Platinum-resistant Urothelial Carcinoma: Efficacy, Safety, and Biomarker Analyses with Extended Follow-up from CheckMate 275.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2020
Galsky Matthew D, Saci Abdel, Szabo Peter M, Han G Celine, Grossfeld Gary, Collette Sandra, Siefker-Radtke Arlene, Necchi Andrea, Sharma Padmanee
Abstract excerpt
PURPOSE: We report efficacy and safety with extended follow-up, and exploratory biomarker analyses from the phase II CheckMate 275 trial to identify biomarkers of response to nivolumab in platinum-resistant metastatic or unresectable urothelial carcinoma (mUC). PATIENTS AND METHODS: Patients received nivolumab 3 mg/kg once every 2 weeks until disease progression, unacceptable toxicity, or other protocol-defined...
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