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Article

Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole-genome sequencing.

Journal of medical virology - 1 Nov 2020

Chan Wan-Mui, Ip Jonathan Daniel, Chu Allen Wing-Ho, Yip Cyril Chik-Yan, Lo Lap-Sum, Chan Kwok-Hung, Ng Anthony Chin-Ki, Poon Rosana Wing-Shan, To Wing-Kin, Tsang Owen Tak-Yin, Leung Wai-Shing, Kwan Mike Yat-Wah, Chua Gilbert T, Chung Tom Wai-Hin, Hung Ivan Fan-Ngai, Kok Kin-Hang, Cheng Vincent Chi-Chung, Chan Jasper Fuk-Woo, Yuen Kwok-Yung, To Kelvin Kai-Wang

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) pandemic. Accurate detection of SARS-CoV-2 using molecular assays is critical for patient management and the control of the COVID-19 pandemic. However, there is an increasing number of SARS-CoV-2 viruses with mutations at the primer or probe binding sites, and these mutations may affect the sensitivity...

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Source

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Identifiers

PMID: 32501535
DOI: 10.1002/jmv.26140
PMCID: PMC7300711

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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