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Article

Systems Genetics for Mechanistic Discovery in Heart Diseases.

Circulation research - 5 Jun 2020

Rau Christoph D, Lusis Aldons J, Wang Yibin

Abstract excerpt

Cardiovascular diseases are the leading cause of death worldwide. Complex diseases with highly heterogenous disease progression among patient populations, cardiovascular diseases feature multifactorial contributions from both genetic and environmental stressors. Despite significant effort utilizing multiple approaches from molecular biology to genome-wide association studies, the genetic landscape of...

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Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Heart Diseases
Systems Biology

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PMID: 32496909
DOI: 10.1161/CIRCRESAHA.119.315863
PMCID: PMC7286104

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