Article
Exploration of a novel prognostic risk signatures and immune checkpoint molecules in endometrial carcinoma microenvironment.
Genomics - 1 Sept 2020
Liu Jinhui, Nie Sipei, Wu Zhipeng, Jiang Yi, Wan Yicong, Li Siyue, Meng Huangyang, Zhou Shulin, Cheng Wenjun
Abstract excerpt
In this study, we devoted to investigate immune-related genes and tumor microenvironment (TME) in EC based on The Cancer Genome Atlas (TCGA) database. In total 799 up-regulated and 139 down-regulated immune-related and differentially expressed genes in EC were investigated for functional annotations and prognosis. By a conjoint Cox regression analysis, we built two risk models for OS and DFS, as well as the...
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