Article
Bevacizumab or PARP-Inhibitors Maintenance Therapy for Platinum-Sensitive Recurrent Ovarian Cancer: A Network Meta-Analysis.
International journal of molecular sciences - 27 May 2020
Bartoletti Michele, Pelizzari Giacomo, Gerratana Lorenzo, Bortot Lucia, Lombardi Davide, Nicoloso Milena, Scalone Simona, Giorda Giorgio, Baldassarre Gustavo, Sorio Roberto, Puglisi Fabio
Abstract excerpt
INTRODUCTION: Targeted agents such as bevacizumab (BEV) or poly (ADP-ribose) polymerase inhibitors (PARPi) which have been added as concomitant or maintenance therapies have been shown to improve progression-free survival (PFS) in patients with platinum-sensitive recurrent ovarian cancer (PS rOC). In the absence of direct comparison, we performed a network meta-analysis considering BRCA genes status. METHODS: We...
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