Article
Identification and functional characterization of a novel acetyl-CoA carboxylase mutation associated with ketoenol resistance in Bemisia tabaci.
Pesticide biochemistry and physiology - 1 Jun 2020
Lueke Bettina, Douris Vassilis, Hopkinson Jamie E, Maiwald Frank, Hertlein Gillian, Papapostolou Kyriaki-Maria, Bielza Pablo, Tsagkarakou Anastasia, Van Leeuwen Thomas, Bass Chris, Vontas John, Nauen Ralf
Abstract excerpt
Insecticides of the tetronic/tetramic acid family (cyclic ketoenols) are widely used to control sucking pests such as whiteflies, aphids and mites. They act as inhibitors of acetyl-CoA carboxylase (ACC), a key enzyme for lipid biosynthesis across taxa. While it is well documented that plant ACCs targeted by herbicides have developed resistance associated with mutations at the carboxyltransferase (CT) domain,...
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