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Long noncoding RNA MALAT1 inhibits the apoptosis and autophagy of hepatocellular carcinoma cell by targeting the microRNA-146a/PI3K/Akt/mTOR axis

13 May 2020

Abstract excerpt

Abstract Background Increased long noncoding RNA (lncRNA) expression is characteristic to hepatocellular carcinoma (HCC) and several other neoplasms. The present study aimed to identify the mechanism underlying modulation of HCC development by the lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1). Methods Quantitative real-time polymerase chain reaction was used to determine MALAT1 and...

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PMID: 32435156
DOI: 10.1186/s12935-020-01231-w

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