Article
Epidemiology of Adenovirus Infections and Outcomes of Cidofovir Treatment in Severely Ill Children.
The Pediatric infectious disease journal - 1 Oct 2020
Siew Jia Xuan, Seah Xue Fen Valerie, Chew Yi Rong, Thoon Koh Cheng, Chong Chia Yin, Yung Chee Fu, Maiwald Matthias, Len Ye, Li Jiahui, Kam Kai Qian, Nadua Karen, Tanugroho Raymond, Tan Natalie Woon Hui
Abstract excerpt
BACKGROUND: An increase in human adenovirus (HAdV) infections among hospitalized children in Singapore was observed since 2013. Young age (<2 years) and significant comorbidities have been associated with severe HAdV infections which can result in significant morbidity and mortality. Cidofovir (CDV) has been used to treat severe HAdV infections despite limited data and efficacy. METHODS: This is a retrospective,...
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