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Article

Transcriptome profiling reveals insertional mutagenesis suppressed the expression of candidate pathogenicity genes in honeybee fungal pathogen, Ascosphaera apis.

Scientific reports - 5 May 2020

Getachew Awraris, Abejew Tessema Aynalem, Wu Jiangli, Xu Jin, Yu Huimin, Tan Jing, Wu Pengjie, Tu Yangyang, Kang Weipeng, Wang Zheng, Xu Shufa

Abstract excerpt

Chalkbrood disease is caused by Ascosphaera apis which severely affects honeybee brood. Spore inoculation experiments shown pathogenicity varies among different strains and mutants, however, the molecular mechanism of pathogenicity is unclear. We sequenced, assembled and annotated the transcriptomes of wild type (SPE1) and three mutants (SPE2, SPE3 and SPE4) with reduced pathogenicity that were constructed in our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32372055
DOI: 10.1038/s41598-020-64022-3
PMCID: PMC7200787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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