Article
Autoimmunity-Related Risk Variants in PTPN22 and CTLA4 Are Associated With ME/CFS With Infectious Onset.
Frontiers in immunology - 1 Jan 2020
Steiner Sophie, Becker Sonya C, Hartwig Jelka, Sotzny Franziska, Lorenz Sebastian, Bauer Sandra, Löbel Madlen, Stittrich Anna B, Grabowski Patricia, Scheibenbogen Carmen
Abstract excerpt
Single nucleotide polymorphisms (SNP) in various genes have been described to be associated with susceptibility to autoimmune disease. In this study, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients and controls were genotyped for five immune gene SNPs in tyrosine phosphatase non-receptor type 22 (PTPN22, rs2476601), cytotoxic T-lymphocyte-associated protein 4 (CTLA4, rs3087243), tumor...
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