Article
Correlation between initial tumour volume and treatment duration on Dabrafenib: observation study of subjects with BRAF mutant melanoma on the BRF112680 trial.
BMC cancer - 22 Apr 2020
Ali Arwa, Dumbrava Monica, Riddell Kylie, Stewart Nina, Ward Robyn, Ibrahim Ahmed K, Chin Melvin
Abstract excerpt
BACKGROUND: Planar-based measurements of lesions in metastatic melanoma have limitations in estimating tumor burden of a patient and in predicting response to treatment. Volumetric imaging might add predictive value to Response criteria in Solid Tumor (RECIST)-measurement. Based on clinical observations, we explored the association between baseline tumor volume (TV) and duration of treatment with dabrafenib in...
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