Article
CLINICAL CHARACTERISTICS AND NATURAL HISTORY OF RHO-ASSOCIATED RETINITIS PIGMENTOSA: A Long-Term Follow-Up Study.
Retina (Philadelphia, Pa.) - 1 Jan 2021
Nguyen Xuan-Thanh-An, Talib Mays, van Cauwenbergh Caroline, van Schooneveld Mary J, Fiocco Marta, Wijnholds Jan, Ten Brink Jacoline B, Florijn Ralph J, Schalij-Delfos Nicoline E, Dagnelie Gislin, van Genderen Maria M, de Baere Elfride, Meester-Smoor Magda A, De Zaeytijd Julie, Balikova Irina, Thiadens Alberta A, Hoyng Carel B, Klaver Caroline C, van den Born L Ingeborgh, Bergen Arthur A, Leroy Bart P, Boon Camiel J F
Abstract excerpt
PURPOSE: To investigate the natural history of RHO-associated retinitis pigmentosa (RP). METHODS: A multicenter, medical chart review of 100 patients with autosomal dominant RHO-associated RP. RESULTS: Based on visual fields, time-to-event analysis revealed median ages of 52 and 79 years to reach low vision (central visual field <20°) and blindness (central visual field <10°), respectively. For the best-corrected...
Topics
- Acute-Phase Proteins
- Aged
- Electroretinography
- Female
- Follow-Up Studies
- Forecasting
- Humans
- Male
- Middle Aged