Article
First-line immune checkpoint therapy in metastatic squamous cell lung cancer harboring both EGFR mutation and high expression of PD-L1: A case report.
Thoracic cancer - 1 Jun 2020
Hamai Kosuke, Tanahashi Hiroki, Ueno Sayaka, Konishi Hanae, Matsumura Mirai, Nomura Akio, Nakamoto Kanako, Isoyama Shoko, Tanimoto Takuya, Shoda Hiroyasu, Ishikawa Nobuhisa
Abstract excerpt
A 90-year-old female was admitted to our hospital with a history of a dry cough. Chest computed tomography (CT) scan showed a tumor shadow, and CT-guided lung biopsy revealed squamous cell carcinoma harboring an EGFR mutation. In addition, programmed death-ligand 1 (PD-L1) was highly expressed with a tumor proportion score (TPS) of >75%. Pembrolizumab therapy in the first-line setting was not effective, and the...
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