Article
Molecular Diagnostics of Cystic Fibrosis in Serbia: Our Approach to Meet the Diagnostic Challenges.
Genetic testing and molecular biomarkers - 1 Apr 2020
Divac Rankov Aleksandra, Kusic-Tisma Jelena, Ljujic Mila, Nikolic Aleksandra, Milosevic Katarina, Vilotijevic Dautovic Gordana, Radojkovic Dragica
Abstract excerpt
Background: High heterogeneity levels of cystic fibrosis transmembrane regulator (CFTR) are manifested in different populations. The aim of this study was to analyze comprehensively all mutations in the CFTR gene in Serbian patients with cystic fibrosis (CF) and to use the findings to propose a testing algorithm for the Serbian population. Materials and Methods: Cascade screening was employed to detect mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.