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Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis

1 Mar 2020

Abstract excerpt

BACKGROUND: Paclitaxel (PTX) is one of the widely used chemotherapy drugs in breast cancer (BC) treatment. Unfortunately, the survival rate of metastatic BC patients remains poor due to PTX resistance. Therefore, uncovering the underlying mechanism behind the PTX resistance of BC cells is crucial for BC therapy. METHODS: The enrichment of circular RNA ATP binding cassette subfamily B member 10 (circ-ABCB10),...

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PMID: 32273769
DOI: 10.2147/cmar.s238513

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