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Article

Pregnancy associates with alterations to the host and microbial proteome in vaginal mucosa

20 Mar 2020

Abstract excerpt

PROBLEM: Pregnant women are at increased risk of HIV acquisition, but the biological mechanisms contributing to this observation are not well understood. METHOD OF STUDY: Here, we assessed host immune and microbiome differences in the vaginal mucosa of healthy pregnant and non-pregnant women using a metaproteomics approach. Cervicovaginal lavage (CVL) samples were collected from 23 pregnant and 25 non-pregnant...

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PMID: 32196803
DOI: 10.1111/aji.13235

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