Article
Vitamin D Metabolism Is Dysregulated in Asthma and Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine - 1 Aug 2020
Jolliffe David A, Stefanidis Christos, Wang Zhican, Kermani Nazanin Z, Dimitrov Vassil, White John H, McDonough John E, Janssens Wim, Pfeffer Paul, Griffiths Christopher J, Bush Andrew, Guo Yike, Christenson Stephanie, Adcock Ian M, Chung Kian Fan, Thummel Kenneth E, Martineau Adrian R
Abstract excerpt
Rationale: Vitamin D deficiency is common in patients with asthma and chronic obstructive pulmonary disease (COPD). Low 25-hydroxyvitamin D (25[OH]D) levels may represent a cause or a consequence of these conditions.Objectives: To determine whether vitamin D metabolism is altered in asthma or COPD.Methods: We conducted a longitudinal study in 186 adults to determine whether the 25(OH)D response to six oral doses...
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