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Article

Next-Generation Radiogenomics Sequencing for Prediction of EGFR and KRAS Mutation Status in NSCLC Patients Using Multimodal Imaging and Machine Learning Algorithms.

Molecular imaging and biology - 1 Aug 2020

Shiri Isaac, Maleki Hasan, Hajianfar Ghasem, Abdollahi Hamid, Ashrafinia Saeed, Hatt Mathieu, Zaidi Habib, Oveisi Mehrdad, Rahmim Arman

Abstract excerpt

PURPOSE: Considerable progress has been made in the assessment and management of non-small cell lung cancer (NSCLC) patients based on mutation status in the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS). At the same time, NSCLC management through KRAS and EGFR mutation profiling faces challenges. In the present work, we aimed to evaluate a comprehensive radiomics framework...

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PMID: 32185618
DOI: 10.1007/s11307-020-01487-8

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